By Albert Folch
The whole scope of the BioMEMS field—at your fingertips
Helping to coach the recent new release of engineers and biologists, Introduction to BioMEMS explains how convinced difficulties in biology and medication reap the benefits of and sometimes require the miniaturization of units. The publication covers the complete breadth of this dynamic box, together with classical microfabrication, microfluidics, tissue engineering, cell-based and noncell-based units, and implantable structures. It makes a speciality of high-impact, inventive paintings encompassing the entire scales of life—from biomolecules to cells, tissues, and organisms.
Brilliant colour presentation
Avoiding the overpowering information present in many engineering and physics texts, this groundbreaking book—in colour throughout—includes basically the main crucial formulation in addition to many noncalculation-based routines. very important phrases are highlighted in daring and outlined in a thesaurus. The textual content includes greater than four hundred colour figures, so much of that are from the unique researchers.
Coverage of either old views and the newest developments
Developed from the author’s long-running direction, this classroom-tested textual content provides readers a shiny photo of ways the sector has grown by means of proposing ancient views and a timeline of seminal discoveries. It additionally describes quite a few cutting-edge biomedical purposes that take advantage of "going small," together with units that checklist task of mind cells, degree the diffusion of molecules in microfluidic channels, and make allowance for high-throughput experiences of gene expression.
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Additional info for Introduction to BioMEMS
After much internal struggle, I decided to delete a beautiful section on fabric microfluidics that reviewed a fascinating new field: the fabric devices, which have features on the millimeter scale, don’t quite make the miniaturization cutoff that is required to enter the above “BioMEMS” definition. ) is that fabric will never outcompete paper in terms of manufacturing cost and versatility when it comes to deploying molecular assays. For the sake of the students, I had to stop somewhere. The greatest lasting value of this book probably rests in the quality of the figures, most of which are original figures (even if they refer to older work).
1 Why Bother Making Things Small? 1. Microfabrication techniques are beneficial to biomedical applications mostly for three reasons. 1 The Small-Scale Benefit First, miniaturization allows for addressing a small unit, whose unique function is inherently determined by its size. In microelectronics, an example of such a unit is a transistor; the switching performance of the transistor is enhanced by its smallness. For micromechanical parts, such as the accelerometer inside an airbag deployer, or a fluidic valve, the smaller they are in size, the faster they react, the less energy they require to operate, and the less sensitive they are to ambient vibrations.
5. , an opaque pad of metal) on unexposed SU-8. Thus, the areas shadowed by the pad are not cross-linked by subsequent exposures to light (of that layer or subsequently spun layers). 5 Biocompatible Photoresists Most types of photoresists are not biocompatible—cells die when cultured on top of them and they are not authorized for use in implantable devices. However, there are some notable exceptions: photosensitive poly(dimethyl siloxane) (PDMS), Ormocer, and water-soluble photo resists based on poly (N-isopropylacrylamide) (poly-NIPAM).