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Extra info for Environmental Aspects of Textile Dyeing Publisher
2 represent a health risk to consumers and should cease to be used for clothes (Hunger, 2003). Currently, there is no legal prohibition on these dyes in any country but some organisations, such as the International Association for Research and Testing in the Field of Textile Ecology, which bestows eco-labels on environmentally and toxicologically proven textiles, refuses eco-labels for some dyes (Oko-Tex, 2000). 4 Chronic toxicity of textile dyes Genotoxicity is the major long-term potential health hazard of certain textile dyes.
Mutagenic chemicals may or may not be carcinogens (cause cancer) in animals and humans. However, since the Ames test is a highly sensitive assay for the induction of point mutations in bacteria, rather than a test for the complex multiple-step process of carcinogenesis in mammals, a close correlation between the Ames test results and rodent cancer assays cannot be expected (ETAD, 1998). Validation studies (Ashby, 1989) show a fairly low degree of correlation between mutagenicity in bacteria and carcinogenicity in rodents.
Because trace levels of some compounds may be present in products used or because limited exposures are not considered harmful, OEHHA has developed safe harbor numbers. A business can declare ‘safe harbor’ from Proposition 65 warning requirements if exposure to a chemical occurs at or below these levels. These safe harbor numbers consist of no significant risk levels for chemicals listed as causing cancer and maximum allowable dose levels for chemicals listed as causing birth defects or other reproductive harm.